Congratulations to Dr. Jessica Caballero on her dissertation defense and PhD. We wish her luck in her new position at Genentech.
Postdoc position available to work on frontal cortex circuits and behavior. Check out “Join the Lab” for more info.
New people news – Tyler Carey begins as a new research assistant in the lab, joining Nadia Alexandrou-Majaj (who started last summer, but never got an announcement). Welcome to these outstanding junior scientists!
Alumni news – Dr. Beata Kaminska has started her new position at Dicerna
Funding news – the Moorman Lab was awarded an R21 from NIMH to study medial prefrontal cortex neural circuits in action control. New hiring listings coming soon.
Publication news – new review on prefrontal encoding of value and action with Dr. Beata Kaminska and Jessica Caballero. This was a chapter in an amazing book organized by Amarante, Brockett, Laubach, and Roesch. Check it out here
More big lab news! Congratulations to Dr. Beata Kaminska, PhD @Beata_Kamins, on her successful dissertation defense, first-ever outdoors socially-distanced thesis defense talk (at least that we’ve ever seen), and amazing data – coming soon to multiple papers near you!
John’s paper is online at eNeuro! And check out this neat article about our work.
Also, Rosalind Carney at eNeuro has written an awesome Research Highlight about Jessica’s paper from last year.
New publications (updates on publication page to come. Congrats to all of the hard-working authors!):
Hernandez, Rahman, Tarantino, and Moorman – Orbitofrontal cortex inactivation decreases cue-induced reinstatement for ethanol and sucrose. Accepted at Alcoholism: Clinical and Experimental Research
den Hartog, Blandino, Nash, Sjogren, Grampetro, Moorman, and Vazey – Noradrenergic tone mediates marble burying behavior after chronic stress and ethanol. Accepted at Psychopharmacology
UMass College of Natural Sciences Seed Grant
Arinze and Moorman 2020 – Selective Impact of Lateral Orbitofrontal Cortex Inactivation on Reinstatement of Alcohol Seeking in Male Long-Evans Rats ( https://pubmed.ncbi.nlm.nih.gov/32092436)
Hernandez and Moorman 2020 – Orbitofrontal cortex encodes preference for alcohol. Accepted at eNeuro
NSF #1942176 – CAREER: Frontal cortical ensemble regulation of response execution and inhibition
See details here
We are recruiting new lab members to participate in this exciting new line of work
Come see presentations by Moorman lab members at the 2019 Society for Neuroscience Conference:
Monday – Oct. 21, 2019, 1:00 PM – 5:00 PM
414.17 – Prefrontal and orbitofrontal cortex neurons are differentially activated during passive and active alcohol acquisition: Influences of individual preference and chronic exposure
B. KAMINSKA, M. L. BERKOWITZ-CERASANO, D. E. MOORMAN
Tuesday – Oct. 22, 2019, 8:00 AM – 12:00 PM
494.20 – Role of rat secondary motor cortex in complex movements and decision making
A. BURMAN, E. M. VAZEY, D. E. MOORMAN;
Tuesday – Oct. 22, 2019, 8:00 AM – 12:00 PM
504.11 – Characterization of prefrontal-subcortical circuitry in execution and inhibition of reward seeking behaviors
J. P. CABALLERO, D. E. MOORMAN;
More exciting lab news: Congratulations to Jessica Caballero on her recently-accepted paper in eNeuro!
BIG LAB NEWS! Congratulations to our first PhD Alum Dr. John Hernandez! John successfully defended his dissertation and is off to do his postdoc in the lab of Dr. Karla Kaun at Brown University. Well done Dr. Hernandez!
Jessica Caballero was awarded a Dissertation Grant from the National Center for Responsible Gaming. She will use this award to further her studies on the role of the prefrontal cortex in action control. Congratulations Jessica!
Come see presentations by members of the Moorman lab (and Moorman/Vazey lab) at the 2018 Society for Neuroscience conference:
Sunday, November 4, 2018, 10:00 AM – 11:00 AM
Session 163 – Animal Cognition and Behavior: Executive Function: Learning and Memory I
163.15 / DDD14 – Do medial prefrontal neurons encode predicted value of a cue or the action elicited by a cue during classical conditioning?
Sunday, November 4, 2018, 1:00 PM – 2:00 PM
Session 242 – Animal Cognition and Behavior: Executive Function: Inhibitory Control
242.13 / DDD8 – Influence of medial prefrontal subregion inactivation on action control using a variable ratio go/no-go task
Carol den Hartog
Tuesday, November 6, 2018, 4:00 PM – 5:00 PM
Session 601 – Drugs of Abuse and Addiction: Alcohol: Neural Mechanisms II
601.20 / GGG16 – Effects of chronic ethanol and stress on spontaneous and sensory-evoked responses of locus coeruleus noradrenergic neurons
Wednesday, November 7, 2018, 2:00 PM – 3:00 PM
Session 782 – Subcortical Mechanisms in Motivated Behaviors and Physiological States
782.18 / GGG19 – Target-specific effects of hypocretin/orexin neuron activation on seeking-taking behavior in the rat
New publication in collaboration with Elena Vazey and Gary Aston-Jones in PNAS!
In other great news, the Moorman lab was awarded a Neural and Cognitive Systems grant from NSF, in collaboration with Guangyu Xu and Genglin Li, from UMass Amherst, and Ethan Meyers from Hampshire College. Very excited about this collaborative work
POSTDOC POSITION AVAILABLE. Please see “Join the lab” for details.
It is with great pride and sadness that we bid a fond farewell to Samantha Rios, who is leaving us to begin her graduate career in neuroscience at OHSU. We also say goodbye to Ellen Rodberg, from the Vazey Lab (a onetime Moorman Lab member), who is starting graduate school in neuroscience at the University of Michigan.
Fortunately, we have found an excellent new lab-manager/research assistant in Maddy Berkowitz-Cerasano, who joins us as a recent alum of Mount Holyoke College. Maddy is already off to an incredible start getting the lab in shape and making progress on some of our orbitofrontal cortex studies. Welcome Maddy!
As always, David is behind in updating the Lab Members page, but promises that he’ll get to it ASAP.
New reviews from the Moorman and Vazey Labs out now – all related to alcohol use and the orbitofrontal cortex, the hypocretin/orexin and dynorphin systems, and the locus coeruleus noradrenergic system. Up next – get ready for some awesome papers from Jessica and John from the Moorman Lab and a collaboration with the Vazey Lab (coming soon!).
Congratulations to our graduating seniors – Sherry Ye, who will be starting the Neuroscience Graduate Program at Emory this fall, and Stephanie Fedorchak, who will be starting the Neuroscience Graduate Program at UTHSCSA. Sherry will be joined at Emory by Vazey Lab alum Michael Kelberman. So much neuro-greatness! We are looking forward to having these future neuroscientists as colleagues in the coming years. Congrats also to Myeongseong Jong who is off to medical school in Singapore!
We also welcome Ariel Burman, a graduate student in Neuroscience at the Engineering School in University of Buenos Aires, Argentina, under the direction of Dr. Sergio Lew and Dr. Silvano Zanutto. Ariel is joining us for the summer/fall on a Fulbright Scholarship. He will be working on neurophysiological studies of motor control and decision making. We are very happy he is joining us!
More info coming soon, including updates on this year’s SfN presentations from the Moorman Lab.
Come see the Moorman Lab at SfN in Washington DC:
On Saturday, 11/11 John Hernandez will present his results on DREADD inactivation of OFC neurons during alcohol seeking and Samantha Rios will present her data on individual differences in alcohol taste reactivity.
On Sunday, 11/12 Jessica Caballero will present her study of dorsal vs. ventral mPFC inactivation and reward seeking.
On Monday, 11/13 Beata Kaminska will present her findings involving mPFC neuronal activity during appetitive and aversive conditioning.
Finally, on Tuesday, 11/14, come see the minisymposium on the Functional Diversity of Prefrontal Cortical Regions and Networks, chaired by David (who will present, too).